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Blueprinting the regulatory response of Escherichia coli to the urinary tract.

Seed PC, Hultgren SJ

Department of Pediatrics, Washington University School of Medicine, St. Louis, MO, 63110, USA.

Recent work has shown how comparative genomic and microarray analyses can provide insights into the transcriptional state of uropathogenic Escherichia coli (UPEC) during infection. This study will serve as an important platform from which to identify virulence determinants and the principle mechanisms of adaptation to the urinary tract.

Published 6 June 2005 in Trends Microbiol, 13(6): 246-8.
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