Cranberry Research Today is a free monthly online journal that collates and summarizes the latest research about Cranberry, including details on benefits, antioxidants, utis, cystitis.

Urinary interleukin-8 is elevated in urinary tract infections independently of the causative germs.

Oregioni O, Delaunay P, Bruna P, Gaudart A, Lemichez E, Boquet P, Landraud L

Laboratoire de Bactériologie, CHU de Nice, France. oregioni.o@chu-nice.fr

Interleukin-8 elevation in urine during urinary tract infections (UTIs) has been documented for different uropathogenic germs in 85 patients. We showed that for 17 different isolates, IL-8 was increased in 92% of UTIs with an average value of 627 pg/ml for infected, as compared to 45 pg/ml for uninfected patients. We suggest that the high negative predictive value of the IL-8 urine assay could be useful to eliminate UTIs in routine screenings.

Published 6 September 2005 in Cytokine, 31(6): 415-8.
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